• Live high, train low - influence on resting and post-exercise hepcidin levels

      Govus, Andrew; Peeling, P.; Abbiss, Chris R.; Lawler, N.G.; Swinkels, D.W.; Laarakkers, C.M.; Thompson, K.G.; Peiffer, Jeremiah J.; Gore, C.J.; Garvican-Lewis, L.A. (2016-03-31)
      ) was measured via CO rebreathing 1 week before and after 14 days of hypoxia. Hepcidin was suppressed after 2 (Cohen's d = -2.3, 95% confidence interval: [-2.9, -1.6]) and 14 days of normobaric hypoxia (d = -1.6 [-2.6, -0.6]). Hepcidin increased from baseline, 3 h post-exercise in normoxia (d = 0.8 [0.2, 1.3]) and hypoxia (d = 0.6 [0.3, 1.0]), both before and after exposure (normoxia: d = 0.7 [0.3, 1.2]; hypoxia: d = 1.3 [0.4, 2.3]). In conclusion, 2 weeks of normobaric hypoxia suppressed resting hepcidin levels, but did not alter the post-exercise response in either normoxia or hypoxia, compared with the pre-exposure response.