• Fabrication and transfer printing of periodic Pt nanonetwork gratings

      Yu, Miao; Li, Li; Wu, Xiaomin; Song, Yingying; Liu, Jinyun; Wang, Zuobin; Changchun University of Science and Technology; University of Bedfordshire (AIP Publishing, 2020-03-13)
      Metal nanonetworks are applied in various applications, such as biomedicine, bionic materials, optical materials, and new energy materials. Here, periodic variable-sized Pt nanonetwork gratings (PtNGs) are fabricated on the surface of a Pt/Si substrate with single pulse two-beam direct laser interference lithography. The fabricated PtNGs are transferred onto the surface of a glass substrate with polymethyl methacrylate as the transfer mediator. Exposure with different film thicknesses, contrasts, and intensity distributions of the laser interference spot is analyzed, and the formation of nanopatterns is explained. Results show that with the change in the thicknesses of the Pt film, the exposed structures present Pt nanoparticles (PtNPs), Pt gratings, and PtNGs. The morphology and the feature size of the PtNGs are influenced by intensity distributions and the contrast of the laser interference spot significantly.
    • In situ lift-off of InAs quantum dots by pulsed laser irradiation

      Deng, Changwei; Shi, Zhenwu; Yang, Linyun; Zhang, Wei; Chen, Chen; Miao, Lili; Yang, Xinning; Wang, Chinhua; Chen, Linsen; Peng, Changsi; et al. (AIP Publishing, 2018-08-24)
      InAs/GaAs quantum dots (QDs) grown by molecular beam epitaxy were subjected to in situ irradiation using a mono-beam pulsed laser. The evolution of the QD morphology was investigated as a function of irradiation intensity at temperatures of 525 °C and 480 °C. The temperature was found to exert a considerable influence on the reaction of the QDs to the irradiation. At the higher temperature (525 °C), both the height and width of the InAs QDs gradually decreased with increasing irradiation intensity, which was ascribed to the dominant effect of the laser desorption of indium. In contrast, at the lower temperature (480 °C), the height of the InAs islands decreased with increasing irradiation intensity while the width exhibited unexpected broadening, which was attributed to a combination of laser desorption and laser diffusion of indium. Remarkably, at the higher temperature, laser irradiation above a certain threshold intensity resulted in the lift off of the InAs QDs to afford a clear, smooth, and perfect GaAs surface. Through subsequent growth of QDs on this surface, it was found that the QDs exhibited the same nucleation properties and optical quality as the common Stranski–Krastanov mode on an as-prepared GaAs surface. Therefore, we have developed a technology for the damage-resistant fabrication of QDs using in situ pulsed laser irradiation (LIR), which is expected to find potential applications in the manufacture of patterned QDs upon upgrading the mono-beam irradiation to multi-beam interference irradiation in the future.
    • In-situ laser nano-patterning for ordered InAs/GaAs(001) quantum dot growth

      Zhang, Wei; Shi, Zhenwu; Huo, Dayun; Guo, Xiaoxiang; Zhang, Feng; Chen, Linsen; Wang, Qinhua; Zhang, Baoshen; Peng, Changsi; Soochow University; et al. (AIP Publishing, 2018-04-12)
      A study of in-situ laser interference nano-patterning on InGaAs wetting layers was carried out during InAs/GaAs (001) quantum dot molecular beam epitaxy growth. Periodic nano-islands with heights of a few atomic layers were obtained via four-beam laser interference irradiation on the InGaAs wetting layer at an InAs coverage of 0.9 monolayer. The quantum dots nucleated preferentially at edges of nano-islands upon subsequent deposition of InAs on the patterned surface. When the nano-islands are sufficiently small, the patterned substrate could be spontaneously re-flattened and an ordered quantum dot array could be produced on the smooth surface. This letter discusses the mechanisms of nano-patterning and ordered quantum dot nucleation in detail. This study provides a potential technique leading to site-controlled, high-quality quantum dot fabrication.
    • Single-cell patterning technology for biological applications

      Wang, Zihui; Lang, Baihe; Qu, Yingmin; Li, Li; Song, Zhengxun; Wang, Zuobin; ; Changchun University of Science and Technology; University of Bedfordshire (AIP Publishing, 2019-11-11)
      Single-cell patterning technology has revealed significant contributions of single cells to conduct basic and applied biological studies in vitro such as the understanding of basic cell functions, neuronal network formation, and drug screening. Unlike traditional population-based cell patterning approaches, single-cell patterning is an effective technology of fully understanding cell heterogeneity by precisely controlling the positions of individual cells. Therefore, much attention is currently being paid to this technology, leading to the development of various micro-nanofabrication methodologies that have been applied to locate cells at the single-cell level. In recent years, various methods have been continuously improved and innovated on the basis of existing ones, overcoming the deficiencies and promoting the progress in biomedicine. In particular, microfluidics with the advantages of high throughput, small sample volume, and the ability to combine with other technologies has a wide range of applications in single-cell analysis. Here, we present an overview of the recent advances in single-cell patterning technology, with a special focus on current physical and physicochemical methods including stencil patterning, trap- and droplet-based microfluidics, and chemical modification on surfaces via photolithography, microcontact printing, and scanning probe lithography. Meanwhile, the methods applied to biological studies and the development trends of single-cell patterning technology in biological applications are also described.